Eur J Haematol. Baikal skullcap might also cause sleepiness and drowsiness. Takeshita K, Saisho Y, Kitamura K, et al. WebAllergy Anaphylactic Anorexia Bleeding Ext Bloody Stools Bronchiolitis Cancer Chest Pain Diarrhea Dipsia Dysuria Eczema Eyes Bloodshot Fever Food Allergy [Analysis of main flavonoids contents of Scutellaria baicalensis]. View abstract. Bleeding disorders. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Effects of flavonoids isolated from scutellariae radix on fibrinolytic system induced by trypsin in human umbilical vein endothelial cells. It might cause drowsiness. 1-27-2011;133(2):634-641. View abstract. Allergic contact dermatitis to Tinosorb S, Scutellaria baicalensis, and other emerging allergens in cosmetics. Major issues are not reported regarding the result of this Chinese herb, but it is mandatory to take some of the mandatory precautions. View abstract. Ann Palliat Med. View abstract. View abstract. Efficacy and safety of flavocoxid, a novel therapeutic, compared with naproxen: a randomized multicenter controlled trial in subjects with osteoarthritis of the knee. 1989;35(3):331-335. Mol Nutr Food Res 2008;52(11):1349-1357. Different extracts of this herb have been found to kill cancer cells in the body, but human research is pending in this field. View abstract. Lam, T. L., Lam, M. L., Au, T. K., Ip, D. T., Ng, T. B., Fong, W. P., and Wan, D. C. A comparison of human immunodeficiency virus type-1 protease inhibition activities by the aqueous and methanol extracts of Chinese medicinal herbs. View abstract. Comparison of anti-inflammatory and anti-nociceptive activities of Curcuma wenyujin Y.H. In Vivo 2004;18(4):497-503. Levy RM, Khokhlov A, Kopenkin S, et al. Drug Metab Dispos 2005;33:537-46. It is not an approved drug. View abstract. View abstract. Metformin (Glucophage) is used to help decrease blood sugar. Burnett BP, Jia Q, Zhao Y, Levy RM. View abstract. Zhongguo Zhong.Yao Za Zhi 2010;35(6):682-685. Gao, Z., Huang, K., and Xu, H. Protective effects of flavonoids in the roots of Scutellaria baicalensis Georgi against hydrogen peroxide-induced oxidative stress in HS-SY5Y cells. Planta Med 2002;68(2):128-132. Yuan Y., Liu Y.J, Luo Y.J, and et al. View abstract. Ye, F., Xui, L., Yi, J., Zhang, W., and Zhang, D. Y. Anticancer activity of Scutellaria baicalensis and its potential mechanism. View abstract. Huang, S. T., Wang, C. Y., Yang, R. C., Chu, C. J., Wu, H. T., and Pang, J. H. Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells. Beijing Da.Xue.Xue.Bao. No matter new buyer or old purchaser, We believe in long expression and trusted relationship for Scutellaria Baicalensis Root, Nootropics Modafinil, Herbal Extract Oil, Maca Extract Liquid, Hawthorn Extract Vs Hawthorn Berry. Ding, X. F., Gao, H. N., Guo, X. H., Wang, Z. Toxicol.Appl.Pharmacol 8-1-2011;254(3):221-228. J Ethnopharmacol. 2009;30(11):1505-1512. A medicinal extract of Scutellaria baicalensis and Acacia catechu acts as a dual inhibitor of cyclooxygenase and 5-lipoxygenase to reduce inflammation. Li, T., Li, N., Guo, Q., Ji, H., Zhao, D., Xie, S., Li, X., Qiu, Z., Han, D., Chen, X., and You, Q. Inhibitory effects of wogonin on catalytic activity of cytochrome P450 enzyme in human liver microsomes. 1998;61(2):54-56. 2-1-2010;84(2):137-144. Biol Pharm Bull 2004;27(10):1580-1583. Hui KM, Wang XH, Xue H. Interaction of flavones from the roots of Scutellaria baicalensis with the benzodiazepine site. BMC.Complement Altern Med 2006;6:27. Cancer Chemother.Pharmacol 2011;67(5):1063-1072. Children: Baikal skullcap is POSSIBLY SAFE in children when given intravenously (by IV) by a healthcare provider, short-term. 2010;36(3):329-338. Chang, W. H., Chen, C. H., and Lu, F. J. View abstract. The root has been used Typical doses (see individual product information): Dried herb: 1 to 2 g Konig J, Seithel A, Gradhand U, Fromm MF. View abstract. View abstract. WebThe root of Scutellaria baicalensis is used as medicine. Chen et C. Ling and Scutellaria baicalensis Georgi. CAS #:94279-99-9 | EC #:304-845-9. Planta Med 2010;76(1):76-78. root of Scutellaria baicalensis Georgi. 73.^ Hwang YK, Jinhua M, Choi BR, Cui CA, Jeon WK, Kim H, Kim HY, Han SH, Han JS Effects of Scutellaria baicalensis on chronic cerebral hypoperfusion The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines. But there is not enough information to know if Baikal skullcap is the cause of these side effects. Taking large amounts of Baikal skullcap along with alcohol might cause too much sleepiness. View abstract. 2007;45(3):403-411. Baicalin induces apoptosis via mitochondrial pathway as prooxidant. Sheng, J. P., Chen, H. R., and Shen, L. [Determination of six mineral elements in roots, stems, leaves, flowers and seeds of Scutellaria baicalensis by FAAS]. Ye, F., Jiang, S., Volshonok, H., Wu, J., and Zhang, D. Y. Molecular mechanism of anti-prostate cancer activity of Scutellaria baicalensis extract. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Pneumonitis induced by ou-gon (scullcap). It often is used in combination with other botanicals such as PC-SPES and sho-saiko-to. BMC.Complement Altern Med 2006;6:27. Select a condition to view a list of vitamins. Ann N Y Acad Sci 2007;1095:521-526. Luo, X., Zhou, X., Su, P., and Zhu, W. [Effects of Scutellaria baicalensis stem-leaf total flavonoid on proliferation of vassel smooth muscle cells stimulated by high triglyceride blood serum]. View abstract. Shih, H. C., Hsu, C. S., and Yang, L. L. In vitro study of the tocolytic effect of oroxylin A from Scutellaria baicalensis root. 4 Physical and Chemicals Properties Scutellaria Baicalensis Root Extract In an ultraviolet (UV) spectral analysis of a Scutellaria baicalensis root extract (aqueous ethanol extract), an absorption peak between 200 and 250 nm and an absorption peak between 250 and 300 nm were Dosage: 39 g/day/adult. Yoo, H. H., Park, J. H., and Kwon, S. W. In vitro cytotoxic activity of some Korean medicinal plants on human cancer cell lines: enhancement in cytotoxicity by heat processing. Sasaki, K., Taura, F., Shoyama, Y., and Morimoto, S. Molecular characterization of a novel beta-glucuronidase from Scutellaria baicalensis georgi. View abstract. Acute liver injury due to flavocoxid (Limbrel), a medical food for osteoarthritis: a case series. Elevated high-sensitivity C-reactive protein and high triglycerides were possibly related to ingestion of baicalein tablets in healthy subjects and should be monitored in future studies(25). Shin NR, Gu N, Choi HS, Kim H. Combined effects of Scutellaria baicalensis with metformin on glucose tolerance of patients with type 2 diabetes via gut microbiota modulation. Indian J Med Res 2008;127(6):610-615. A large long-term population study identifies S. barbata among the single herbs used in TCM that may reduce risk of hepatocellular carcinoma in hepatitis B patients(9). Biomed Res Int 2016;2016:5697571. View abstract. Lee, E., Enomoto, R., Suzuki, C., Ohno, M., Ohashi, T., Miyauchi, A., Tanimoto, E., Maeda, K., Hirano, H., Yokoi, T., and Sugahara, C. Wogonin, a plant flavone, potentiates etoposide-induced apoptosis in cancer cells. However, low doses of baicalin upregulated expression of multiple angiogenic genes to increase cell proliferation in developing blood vessels, while high doses inhibited angiogenesis by inducing cell death, suggesting dose-dependent dual effects. Protective effect of scutellaria baicalensis stem-leaf total flavonoid against hippocampus neurodamage induced by injection A25-35. Studies indicate that aqueous extracts suppressed the growth of lymphoma and myeloma cells. J Med Chem 10-21-2004;47(22):5555-5566. In that case, it is either used for hormone synthesis or hormone breakdown, including estrogen and testosterone, which are not advised to combine with the Chinese herb. Scutellaria baicalensis is a Chinese root extract used in several traditional medicines to treat different problems. Shang, Y. Int J Cancer 9-10-2003;106(4):559-565. View abstract. Medications that cause sleepiness are called sedatives. Dry extract of Scutellaria baicalensis as a hemostimulant in antineoplastic chemotherapy in patients with lung cancer. Flavocoxid, a dual inhibitor of cyclooxygenase and 5-lipoxygenase, blunts pro-inflammatory phenotype activation in endotoxin-stimulated macrophages. View abstract. Cancer Res 7-15-2003;63(14):4037-4043. Li L, Gao H, Lou K, et al. Some medications that are moved by these pumps include etoposide, paclitaxel, vinblastine, vincristine, vindesine, ketoconazole, itraconazole, amprenavir, indinavir, nelfinavir, saquinavir, cimetidine, ranitidine, diltiazem, verapamil, corticosteroids, erythromycin, cisapride (Propulsid), fexofenadine (Allegra), cyclosporine, loperamide (Imodium), quinidine, and others. 2019;49(4):544-546. vitamins, herbs, dietary supplements a-z listbaikal skullcap. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Che, Q. M., Huang, X. L., Li, Y. M., Kun, Z., Teruaki, A., and Masao, H. [Studies on metabolites of baicalin in human urine]. 2008;31(5):707-710. Journal of medicinal food 2009;12(5):1143-8. Gasiorowski, K., Lamer-Zarawska, E., Leszek, J., Parvathaneni, K., Yendluri, B. Baicalein: an in vitro antigenotoxic compound from Scutellaria baicalensis. View abstract. View abstract. View abstract. View abstract. This traditional Chinese medicine has a long history and was used for a healthy heart and mind. View abstract. It might cause drowsiness. Chinese Journal of Gerontology 2010;30(7):926-928. View abstract. Zhang S, Cheng Z, Huang B, and Li J. Cancer Treat Rev 2009;35(1):57-68. Efficacy and safety of flavocoxid, a novel therapeutic, compared with naproxen: a randomized multicenter controlled trial in subjects with osteoarthritis of the knee. Immunopharmacology 2000;49:295-306. View abstract. Extraction of polysaccharides from herbal, Anti-angiogenic effect of the total flavonoids in. Levy RM, Saikovsky R, Shmidt E, et al. Chen, Y., Lu, N., Ling, Y., Gao, Y., Wang, L., Sun, Y., Qi, Q., Feng, F., Liu, W., Liu, W., You, Q., and Guo, Q. Wogonoside inhibits lipopolysaccharide-induced angiogenesis in vitro and in vivo via toll-like receptor 4 signal transduction. Rosenbaum, C. C., O'Mathuna, D. P., Chavez, M., and Shields, K. Antioxidants and antiinflammatory dietary supplements for osteoarthritis and rheumatoid arthritis. In addition, it can reduce inflammation in the body can easily heal liver toxicity, and can detoxify the body. Afr J Tradit Complement Altern Med. View abstract. Scutellaria baicalensis root: Uses, Talk with your healthcare provider before using this product if you are taking lithium. Ren S, Cao D., Yang J, and et al. View abstract. The ethyl acetate (EtOAc) extract showed high ROS scavenging ability, and four compounds were subsequently isolated and purified from this extract: baicalin, baicalein, wogonin, and oroxylin A. 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